Irwin D. Bernstein, MD, is chief of the Division of Hematology/Oncology and Bone Marrow Transplant at Seattle Childrens Hospital and professor of pediatrics at the University of Washington School of Medicine. He is director of the Division of Pediatric Hematology/Oncology in the university Department of Pediatrics and head of the Pediatric Oncology Program at Fred Hutchinson Cancer Research Center (FHCRC). Bernstein holds the John R. Hartmann Endowed Chair in Pediatric Oncology/Hematology at Seattle Childrens and is an American Cancer Society professor. He has been a board member for the Leukemia & Lymphoma Society, is chairman of the societys Professional Education Committee and is a member of the Scientific Advisory Board for the University of Minnesota Cancer Center. Bernsteins research interests include normal and leukemic hematopoietic stem cells, antibody targeted therapies for lymphoma and leukemia, and the biology of acute myeloid leukemia. He is principal investigator on a Leukemia & Lymphoma Society SCOR program in immunotherapy of hematologic malignancies, as well as multiple other grants, including a Program Project Grant and a U01 grant as a member of the NHLBI stem cell consortium. Dr. Bernstein's studies which have led to the development of concepts of targeting leukemic stem cells for therapeutic purposes and have led to a novel approach for expanding stem cell numbers in cord blood. This latter approach is being tested in a clinical trial to improve cord blood transplantation. Bernstein also heads NIH-supported grants for career development in pediatric and medical oncology, and for pediatric oncology research training.